M. Maffezzini et al., BENEFITS AND COMPLICATIONS OF LAPAROSCOPIC PELVIC LYMPHADENECTOMY FORDETECTION OF STAGE D1 PROSTATE-CANCER - A MULTICENTER EXPERIENCE, European urology, 27(2), 1995, pp. 135-137
One hundred fifty-eight consecutive patients with clinically localized
prostate cancer were submitted to staging laparoscopic pelvic lymphad
enectomy (LPL) at 5 cooperative centers with one or more of the follow
ing conditions which were considered as risk factors for nodal disease
: clinical stage C (or T3) disease, serum prostate-specific antigen >
20 ng/ml, Gleason sum > 6. The mean number of lymph nodes removed was
11 (range 2-29). Metastases from prostate cancer were found in 41 pati
ents (25.9%). The proportion of lymph node-positive patients increases
significantly with the presence of one, two or three of the condition
s considered as risk factors (p < 0.00005). The benefit of LPL is limi
ted to the lymph node-positive patients who can be spared a second ope
ration.