Asymmetric polyfluorinated ketones R(F)COR are formed by treating vari
ous derivatives of (polyfluoro)alkanoic acids (esters, anhydrides, aci
d chlorides) with lithium tetraalkylaluminates (''ate-complexes''). Th
e highest yields of the ketones (65-78 %) were obtained from (polyfluo
ro)alkanoyl chlorides.