Percutaneous balloon pericardiostomy was performed in eight severely i
ll patients with malignancy (seven patients) and chronic renal failure
(one patient). To investigate the feasibility of balloon pericardiost
omy as a bedside procedure, echocardiography was used in addition to f
luoroscopy in monitoring the procedure. The pericardium was entered fr
om the standard subxiphoid site. An 18 to 25 mm, 3 or 4 cm long, ballo
on catheter, introduced over a stiff guidewire was inflated across the
parietal pericardium. Creation of a pericardial opening was obtained
in each of the eight patients. Bleeding from the needle entry site was
the only complication observed in one patient. The balloon catheter c
ould be localized by echocardiography only in 2/8 cases. Two patients
died, 3 and 14 days after the procedure, from the primary disease; six
patients were still alive at follow-up ranging from 32 to 342 days. N
o recurrence of cardiac tamponade was observed in any patient. Percuta
neous balloon pericardiostomy is efficacious and safe in relieving per
icardial tamponade and preventing its recurrence in severely ill patie
nts. Fluoroscopy is needed to monitor the procedure. The value of echo
cardiography is limited for follow-up controls of pericardial effusion
.