Fewer than 15 cases of cellulitis and subconjunctival abscess after ex
traocular muscle surgery have been reported in detail. In an effort to
provide greater information about this serious complication, the memb
ers of the American Association for Pediatric Ophthalmology and Strabi
smus (AAPO&S) were surveyed and contributed cases were analyzed. Among
the 25 cases of cellulitis, there was a predominance of preschool age
patients and Staphylococcus aureus cultures. Many cases presented aft
er a normal initial postoperative visit. The most common symptoms were
marked swelling and pain. Possible predisposing factors included unsu
spected sinusitis, eye rubbing, and poor hygiene. Two patients had doc
umented bacteremia, but no patient developed endophthalmitis. All case
s resolved on antibiotics, but only five patients were successfully tr
eated with oral antibiotics alone. Periocular infections after extraoc
ular muscle surgery can present after a normal initial postoperative v
isit. Symptoms of marked swelling and pain are cause for closer inspec
tion. S. aureus is the most common organism and oral antibiotics alone
can fail to halt the infection.