4 HUMAN CHROMOSOME-3Q AND CHROMOSOME-4 HUMAN CHROMOSOME-21 LOCI MAP ONTO SHEEP CHROMOSOME-1Q

Eight new loci have been assigned to sheep Chromosome (Chr) 1q by use of a chromosomally characterized minipanel of sheep x hamster cell hyb rids. Four loci, which have been mapped to the distal region of human Chr 3q, are ceruloplasmin (CP), sucrase isomaltase (SI), glucose trans porter 2 (GLUT2), and ectopic viral integration site 1 (EVI1). The oth er four loci, on human Chr 21, include interferon alpha receptor (IFNA R); interferon inducible protein p78, murine (MX1); collagen type VI, alpha 1 (COL6A1); and S100 protein, beta polypeptide (S100B). All of t hese loci, except GLUT2 and MX1, have been mapped onto bovine Chr 1 or are syntenic with loci on this chromosome. The in situ localization o f transferrin (TF) to sheep Chr 1q42-q45 confirms our previous assignm ent of this locus and independently anchors the eight new syntenic loc i to sheep Chr 1q.