The literature reveals that errors of drug administration are a widely
distributed and common occurrence. The frequency of errors and their
underlying causes are discussed, and the literature is surveyed to det
ermine reasons for mistakes and possible remedial measures. Ideas are
drawn from industrial sources to describe a model of preventing mistak
es at source, by making errors impossible. The ideas of Crosby and Shi
ngo are discussed and a 'zero defects philosophy' is described and dev
eloped. This paper attempts to determine if this quality model develop
ed and used in industry can be transferred to the health service, and
concludes that it needs adaptation and cautious application. Recommend
ations are made for improved practices and improvements, both clinical
and managerial. The author recommends a multidisciplinary review of a
ll practices and systems to develop a radically different procedure wi
th no drug errors as its aim. It is questioned whether this is possibl
e in the present health service environment, as this would require sus
tained management commitment to both the idea and the quality system.
However, the author believes that some of the principles can be applie
d as individual quality initiatives.