This report describes a case of right pulmonary artery obstruction cau
sed by a dissecting aneurysm of the thoracic aorta. Initial ventilatio
n-perfusion (V/Q) scan revealed no perfusion to the right lung. Lack o
f right lung perfusion plus other clinical abnormalities led to an ini
tial diagnosis of massive embolism in the right lung. Bilateral pulmon
ary arteriography of the thoracic and abdominal aorta revealed extrins
ic compression of the right pulmonary artery near its origin and the s
uggestion of an ascending aortic dissection. Subsequent ascending aort
ography and computed tomography (CT) confirmed a dissection of the asc
ending aorta. Aortography in the true lumen of the aorta revealed triv
ial aortic insufficiency. These diagnostic procedures cofirmed the pre
sence of an acute dissecting aneurysm of the ascending aorta that caus
ed compression of the right pulmonary artery. The finding of a massive
unilateral segmental defect with normal ventilation upon lung scannin
g does not always ensure a diagnosis of acute pulmonary embolus. Patie
nt presentation with massive unilateral perfusion defect merits furthe
r evaluation with pulmonary arteriography.