GENBANK

The GenBank sequence database incorporates DNA sequences from all avai lable public sources, primarily through the direct submission of seque nce data from authors and from large-scale sequencing projects, Data e xchange with the EMBL Data Library and the DNA Data Bank of Japan help s ensure comprehensive coverage, GenBank continues to focus on quality control and annotation while expanding data coverage and retrieval se rvices, An integrated retrieval system, known as Entrez, incorporates data from the major DNA and protein sequence databases, along with gen ome maps and protein structure information, MEDLINE abstracts from pub lished articles describing the sequences are also included as an addit ional source of biological annotation, Sequence similarity searching i s offered through the BLAST family of programs, All of NCBI's services are offered through the World Wide Web, In addition, there are specia lized server/client versions as well as FTP and e-mail sewer access.