A NOVEL METHOD TO FABRICATE BIOABSORBABLE SCAFFOLDS

An emulsion freeze-drying method for processing porous biodegradable c opolymers of polylactic and polyglycolic acid (PLGA) scaffolds was dev eloped. Scaffold porosity and pore sizes were measured using mercury p orosimetry. Foams with porosity in the range 91-95%, median pore diame ters ranging from 13 to 35 mu m (with larger pore diameters greater th an 200 mu m), and specific pore area in the range 58-102 m(2) g(-1) we re made by varying processing parameters such as water volume fraction , polymer weight percentage and polymer molecular weight. These scaffo lds may find applications as structures that facilitate either tissue regeneration or repair during reconstructive operations.