EVALUATION OF AN ENZYME-IMMUNOASSAY KIT FOR THE DETECTION OF CLOSTRIDIUM-DIFFICILE ENTEROTOXIN

Authors
BOWMAN RA ARROW S CROESE L RILEY TV
Citation
Ra. Bowman et al., EVALUATION OF AN ENZYME-IMMUNOASSAY KIT FOR THE DETECTION OF CLOSTRIDIUM-DIFFICILE ENTEROTOXIN, Pathology, 26(4), 1994, pp. 480-481
Citations number
15
Categorie Soggetti
Pathology
Journal title
Pathology → ACNP
ISSN journal
00313025
Volume
26
Issue
4
Year of publication
1994
Pages
480 - 481
Database
ISI
SICI code
0031-3025(1994)26:4<480:EOAEKF>2.0.ZU;2-2
Abstract
The Premier(TM) Clostridium difficile toxin A enzyme immunoassay (EIA) kit was evaluated for the detection of G. difficile enterotoxin in fe cal samples. A total of 314 samples was tested by culture, cytotoxin d etection and EIA kit. Compared to a combined culture/cytotoxin result the Premier(TM) EIA kit had a sensitivity of 88.3%, a specificity of 1 00%, a predictive value positive of 100% and a predictive value negati ve of 87.4%. Test results were available within 3 hrs providing a rapi d and reliable means of detecting C. difficile enterotoxin.