The Directory of P450-containing Systems on World-Wide Web has been de
signed to facilitate access to electronic resources for all researcher
s working in the field of P450-containing and related enzyme systems.
Currently, it contains the most up-to-date list of sequences of both t
he P450 superfamily and proteins mediating electron transfer to P450,
i.e. NADPH:P450 reductases, specific NAD(P)H:ferredoxin reductases, cy
tochrome b(5) reductases, ferredoxins and cytochromes b(5), and their
homologues. All the referenced sequences are provided with accession n
umbers and links to major sequence databanks: PIR, SWISS-PROT, EMBL/Ge
nBank and PRF. An associated database of steroid substrates and produc
ts of P450-dependent reactions has also been developed.