T. Oshikawa et al., OPTICALLY-ACTIVE DIAZACYCLOPHOSPHAMIDES - NOVEL EFFICIENT REAGENTS FOR THE DETERMINATION OF THE ABSOLUTE-CONFIGURATION OF AMINES AND ALCOHOLS, Journal of the Chemical Society, Chemical Communications, (4), 1995, pp. 435-436
Various amines and alcohols are converted into the corresponding phosp
hamides by the action of optically active diazacyclophosphamidic chlor
ides and absolute configurations of amines and alcohols are readily de
termined by proton and phosphorus NMR of the cyclophosphamides that ar
e formed.