ENANTIOSELECTIVE RADICAL-MEDIATED REDUCTION OF ALPHA-IODOLACTONE USING TRIBUTYLTIN HYDRIDE IN THE PRESENCE OF A CHIRAL AMINE AND A LEWIS-ACID

Authors
MURAKATA M TSUTSUI H HOSHINO O
Citation
M. Murakata et al., ENANTIOSELECTIVE RADICAL-MEDIATED REDUCTION OF ALPHA-IODOLACTONE USING TRIBUTYLTIN HYDRIDE IN THE PRESENCE OF A CHIRAL AMINE AND A LEWIS-ACID, Journal of the Chemical Society, Chemical Communications, (4), 1995, pp. 481-482
Citations number
15
Categorie Soggetti
Chemistry
Journal title
Journal of the Chemical Society, Chemical Communications → ACNP
ISSN journal
00224936
Issue
4
Year of publication
1995
Pages
481 - 482
Database
ISI
SICI code
0022-4936(1995):4<481:ERROAU>2.0.ZU;2-C
Abstract
Enantioselective radical-mediated reduction of alpha-methoxymethyl-alp ha-iododihydrocoumarin 1 using tributyltin hydride is realized in up t o 62% enantiomeric excess (e,e.) (88% chemical yield) by combination o f chiral diamine 2 and magnesium iodide.