MANDIBULOFACIAL DYSOSTOSIS - CASE-REPORT

A case of mandibulofacial dysostosis (Treacher Collins syndrome) is pr esented. Clinical features and skull radiographs revealed typical anom alies associated with the syndrome. Cleft of the soft palate and uneru pted multiple supernumerary teeth were present in this case. No haemat ological, biochemical or immunological abnormalities could be detected in the patient. Pedigree analysis showed an autosomal dominant mode o f transmission of the disease. Chromosomal studies did not reveal any structural or numerical discrepancies.