FAST-ATOM-BOMBARDMENT MASS-SPECTROMETRY OF SOME PHARMACOLOGICALLY RELEVANT ANTHRAQUINONE DERIVATIVES

Authors
MACCIONI E DELOGU G PODDA G PALUMBO M ZAGOTTO G SERAGLIA R TRALDI P
Citation
E. Maccioni et al., FAST-ATOM-BOMBARDMENT MASS-SPECTROMETRY OF SOME PHARMACOLOGICALLY RELEVANT ANTHRAQUINONE DERIVATIVES, Rapid communications in mass spectrometry, 9(2), 1995, pp. 167-174
Citations number
14
Categorie Soggetti
Spectroscopy,"Chemistry Analytical
Journal title
Rapid communications in mass spectrometry → ACNP
ISSN journal
09514198
Volume
9
Issue
2
Year of publication
1995
Pages
167 - 174
Database
ISI
SICI code
0951-4198(1995)9:2<167:FMOSPR>2.0.ZU;2-X
Abstract
mass spectrometric behaviour of some anthraquinone derivatives has bee n studied by fast-atom bombardment ionization. For all the compounds u nder study, a retrosynthetic process, consisting in the cleavage of th e NH-CO bond with hydrogen rearrangement, has been detected. This deco mposition pathway leads to the formation of the protonated molecule of 1,4-diaminoanthraquinone or to the 1-amino-4,5,8-trihydroxy-anthraqui none, representing the basic synthetic elements of the compounds under investigation.