We consider the instanton contributions for the production of a gluon
jet with large transverse momentum in QCD. We find that Mueller's corr
ections corresponding to the rescattering of hard quanta are likely to
remove the contributions of large instantons, making this cross secti
on well defined. This observation generalizes the previous discussion
of instanton effects in deep inelastic scattering and suggests that al
l hard processes in QCD receive hard non-perturbative corrections from
instantons of small size, of order rho similar to 1/(Q alpha(S)).