INTERPRETATION OF HIGH-PASS RESOLUTION PERIMETRY WITH A PROBABILITY PLOT

Background: The interpretation of high-pass resolution perimetry (HRP) fields can be difficult. An age-related probability plot was derived from a known data base to determine whether this improved specificity and sensitivity in early glaucoma detection Methods: Forty glaucoma pa tients with minor field loss and 40 normals of equivalent age and sex underwent HRP. All had previous Humphrey field data available for comp arison. The detection of previously confirmed field defects by HRP was examined using different parameters. Results: Using the age-corrected 95% confidence levels gave the best results, with sensitivity of 82.5 % (33/40) and specificity of 85% (34/40). Using the contour plot yield ed lower sensitivity (67.5%), while subjectively ''eyeballing'' the ri ng printout gave higher sensitivity (90%), but led to poor specificity (72.5%). Conclusion: The use of a probability plot enhances the perfo rmance of HRP. A certain proportion of cases may be missed using one c riterion alone, but combining the information with other indices can i ncrease the yield.