An overview of the state-of-the-art in flow injection analysis (FIA) c
oupled to instruments capable of providing either multidetection and/o
r multi-information is reported. The versatility of FIA endows the hyp
henated instruments with analytical capabilities which increase from s
imple sample introduction to more complex sample handling such as auto
matic dilution and calibration, solvent exchange, derivatization react
ions and on-line separation processes, among others. Unexplored aspect
s of these powerful problem solvers are also discussed.