ESTABLISHMENT OF CARRIER-STATE INFECTION OF A FELINE RENAL-CELL LINE WITH FELINE SYNCYTIAL VIRUS

Although feline syncytial virus (FSV) is normally highly cytopathogeni c in Crandell feline kidney cells, a non-cytopathic persistent infecti on was established in the cells after cocultivation of the initially i nfected cells with uninfected cells 4 times. More than 90% of the pers istently infected cells were positive for FSV antigen, and electron mi croscopy showed that the culture produced morphologically normal FSV. Virus from the carrier culture was infectious, however, the titer of t he virus from the culture was lower than that from the cytocidally inf ected CRFK cells.