Acceptable function of an internal defibrillator can be achieved with
different patch orientations. For patients requiring defibrillator pat
ches concomitant with a cardiac procedure requiring extracorporeal cir
culation, application of one of the patches within the pericardium adj
acent to the right atrium has provided excellent defibrillation thresh
olds. We describe 4 such patients in whom a compressing thrombus subse
quently developed between the patch and the atrium. The thrombus was s
mall and asymptomatic in 1 patient, but caused localized tamponade req
uiring reexploration in 2 patients and a fatal superior vena caval obs
truction in 1. The precise etiology of this serious complication remai
ns unclear, but its occurrence argues against the application of intra
pericardial defibrillator patches in this orientation.