SUPERIOR SAGITTAL SINUS THROMBOSIS AND THYROTOXICOSIS - POSSIBLE ASSOCIATION IN 2 CASES

Background Superior sagittal sinus thrombosis is an uncommon cerebrova scular accident that is frequently associated with diseases that may c ontribute to the development of thrombosis through hypercoagulability, stasis of the local blood stream, and abnormalities of the vessel wal l. In approximately 25% of cases underlying diseases remain unrecogniz ed. Case Descriptions Two patients with superior sagittal sinus thromb osis during a thyrotoxic phase of Graves' disease are described. Both patients presented with hemiplegia, seizures, and a large goiter. Conc lusions The development of superior sagittal sinus thrombosis is multi factorial. Patients with thyrotoxicosis and a large goiter may be pred isposed to the development of superior sagittal sinus thrombosis throu gh hypercoagulability and stasis of the local venous blood flow.