INHIBITION OF THE ENDOTHELIN-CONVERTING ENZYME BY PEPSIN DIGESTS OF FOOD PROTEINS

Authors
OKITSU M MORITA A KAKITANI M OKADA M YOKOGOSHI H
Citation
M. Okitsu et al., INHIBITION OF THE ENDOTHELIN-CONVERTING ENZYME BY PEPSIN DIGESTS OF FOOD PROTEINS, Bioscience, biotechnology, and biochemistry, 59(2), 1995, pp. 325-326
Citations number
11
Categorie Soggetti
Biology,Agriculture,"Biothechnology & Applied Migrobiology","Food Science & Tenology
Journal title
Bioscience, biotechnology, and biochemistry → ACNP
ISSN journal
09168451
Volume
59
Issue
2
Year of publication
1995
Pages
325 - 326
Database
ISI
SICI code
0916-8451(1995)59:2<325:IOTEEB>2.0.ZU;2-8
Abstract
Inhibitory activities toward the endothelin-converting enzyme (ECE) we re detected in pepsin digests of bonito pyrolic appendix and beef, Aft er Sep-Pak C-18 fractionation, this activity from bonito and beef was recovered in the 50% and 25% ethanol fractions, respectively, Activiti es were also recovered in the ultrafiltrate (< 5000 Da), and disappear ed after a pronase treatment. Therefore, these inhibitory activities m ay have peptidic properties.