Jt. Woo et al., CATHESTATINS, NEW CYSTEINE PROTEASE INHIBITORS PRODUCED BY PENICILLIUM-CITRINUM, Bioscience, biotechnology, and biochemistry, 59(2), 1995, pp. 350-352
New cysteine protease inhibitors, named cathestatin A and B, have been
discovered as metabolites of Penicillium citrinum. Cathestatins were
found to be decarbamidoyl analogs of estatins and showed a specific in
hibition for cysteine proteases, Cathestatins suppressed parathyroid h
ormone (PTH)-stimulated Ca-45 release in organ cultures of chick embry
onic calvaria.