POLYMYOSITIS ASSOCIATED WITH KI-1 LYMPHOMA

We report here a case of acute polymyositis associated with a Ki-1 non Hodgkin's lymphoma (NHL). This anaplastic large cell malignant lympho ma was a primary T-cell NHL lymphoma of the bone marrow. The malignant cells expressed the CD30 (Ki-1), CD3, and CD4 antigens, the beta chai n of the interleukin 2 receptor (CD25), and the betaF1 antigen (alpha/ beta T-cell receptor). Chemotherapy and high dose methylprednisolone p ulse therapy were initiated. However, no clinical improvement was noti ced, because the patient rapidly died of an acute respiratory distress syndrome. To our best knowledge, this represents the first case of Ki -1 lymphoma associated with Polymyositis.