Thirty-six healthy patients, ASA 1, aged 16-41 years, scheduled for el
ective plastic surgery were studied to determine if thoracocervical or
lumbar epidural blocks affected the lag time of the pulse oximeter re
sponse. Patients were allocated to receive thoracocervical epidural bl
ock (n = 20) (group 1) (lignocaine 1%) or lumbar epidural block (n = 1
6) (group 2) (lignocaine 1.5%). Epidural block was performed with a 17
-gauge Tuohy needle inserted in the midline between C-4-T-2) vertebrae
in group 1 and between L(3)-S-1 in group 2 and an epidural chatheter
was introduced. Arterial oxygen saturation (SpO(2)) was measured conti
nuously using a Datex pulse oximeter. The lag time of the pulse oximet
er response was measured while breathing oxygen (100%) after breath-ho
lding. Values were obtained 10 min before and 5, 10, 15, 20, 30, and 4
0 min after epidural injection of a test dose. There was a progressive
decrease in the lag time of the pulse oximeter response so that by 30
min after epidural injection the mean (SD) value had decreased from 2
9 (6.1) to 14 (3.4) in Group 1 and 41 (12.8) to 23 (7.9) s in group 2
(p < 0.01).