EPIDURAL-ANESTHESIA, EPHEDRINE AND PHENYLEPHRINE IN A PATIENT TAKING MOCLOBEMIDE, A NEW MONOAMINE-OXIDASE INHIBITOR

Authors
MARTYR JW ORLIKOWSKI CEP
Citation
Jw. Martyr et Cep. Orlikowski, EPIDURAL-ANESTHESIA, EPHEDRINE AND PHENYLEPHRINE IN A PATIENT TAKING MOCLOBEMIDE, A NEW MONOAMINE-OXIDASE INHIBITOR, Anaesthesia, 51(12), 1996, pp. 1150-1152
Citations number
13
Categorie Soggetti
Anesthesiology
Journal title
Anaesthesia → ACNP
ISSN journal
00032409
Volume
51
Issue
12
Year of publication
1996
Pages
1150 - 1152
Database
ISI
SICI code
0003-2409(1996)51:12<1150:EEAPIA>2.0.ZU;2-8
Abstract
We report a case of low thoracic epidural and general anaesthesia in a patient receiving moclobemide, a new selective inhibitor of monoamine oxidase A. Intra-operative hypotension was initially treated with phe nylephrine and then with ephedrine. The short half-life of moclobemide and its modest interaction with direct and indirect acting sympathomi metic drugs permit the use of epidural anaesthesia, since and associat ed hypotension can be safely treated.