Sp. Walker et al., EARLY-CHILDHOOD SUPPLEMENTATION DOES NOT BENEFIT THE LONG-TERM GROWTHOF STUNTED CHILDREN IN JAMAICA, The Journal of nutrition, 126(12), 1996, pp. 3017-3024
The long-term benefits of early childhood supplementation and the exte
nt to which catch-up growth occurs following linear growth retardation
remain controversial. Stunted children (height-for-age < -2 so of NCH
S references, n = 122) recruited from a survey of poor neighborhoods i
n Kingston, Jamaica, participated in a 2-yr randomized, controlled tri
al of supplementation beginning at ages 9-24 mo. A group of 32 non-stu
nted children from the same neighborhoods was also followed. Four year
s after the intervention ended, when children were 7 to 8 y old, there
were no effects of supplementation on any anthropometric measure. Fro
m the end of the trial until follow-up, the children who had been supp
lemented gained 1.2 cm less (P < 0.05) than the non-supplemented child
ren, approximately the same amount as they had gained during the trial
compared with the non-supplemented children. After adjustment for reg
ression to the mean, the height-for-age of stunted children (supplemen
ted and non-supplemented combined) increased from enrollment to follow
-up by 0.31 Z-score (95% CI 0.17, 0.46). The height-for-age of the non
-stunted children also increased (0.96 Z-score; 95% CI 0.70, 1.22). Ou
r results suggest that some catch-up growth is possible even when chil
dren remain in poor environments. Longterm benefits of supplementation
to growth may not be achieved when intervention begins after age 12 m
o in children who have already become undernourished.