PURPOSE/METHODS: A patient with osteitis deformans (Paget's disease) a
nd hemifacial spasm underwent magnetic resonance tomographic angiograp
hy. Bone-modulating bisphosphonates and botulinum injection were admin
istered to treat the hemifacial spasm. RESULTS/CONCLUSIONS: Computed t
omography showed marked temporal bone overgrowth. Magnetic resonance t
omographic angiography showed no vascular compression of the facial ne
rve root. The hemifacial spasm failed to resolve with intravenous pami
dronate. Subsequent botulinum injection rendered the patient spasm fre
e for 22 weeks. Further research on the use of bisphosphonates in the
treatment of pagetoid hemifacial spasm is required.