ASYMMETRIC CREATION OF QUATERNARY CARBON CENTERS BY ENANTIOTOPICALLY SELECTIVE AROMATIC C-H INSERTION CATALYZED BY CHIRAL DIRHODIUM(II) CARBOXYLATES

Authors
WATANABE N OHTAKE Y HASHIMOTO S SHIRO M IKEGAMI S
Citation
N. Watanabe et al., ASYMMETRIC CREATION OF QUATERNARY CARBON CENTERS BY ENANTIOTOPICALLY SELECTIVE AROMATIC C-H INSERTION CATALYZED BY CHIRAL DIRHODIUM(II) CARBOXYLATES, Tetrahedron letters, 36(9), 1995, pp. 1491-1494
Citations number
22
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
36
Issue
9
Year of publication
1995
Pages
1491 - 1494
Database
ISI
SICI code
0040-4039(1995)36:9<1491:ACOQCC>2.0.ZU;2-R
Abstract
A high order of differentiation of enantiotopic benzene rings has been attained by intramolecular aromatic C-H insertion reactions of alpha- diazo ketones catalyzed by dirhodium(II) tetrakis[N-phthaloyl-(S)-phen ylalanate], leading to the formation of (S)-1-alkyl-1-phenyl-2-indanon es containing a chiral quaternary carbon atom with up to 95% ee.