REACTIONS OF BETA-FLUOROVINAMIDINIUM SALT WITH BIFUNCTIONAL HETERO NUCLEOPHILES - A NEW SYNTHETIC ROUTE TO FLUORINATED HETEROCYCLES

beta-Fluorovinamidinium salt (2), readily prepared from N-(2,3,3-trifl uoro-1-propenyl)trimethylammonium iodide (1) and diethylamine, reacted with bifunctional hetero nucleophiles such as amidine and guanidine h ydrochlorides in the presence of a base to afford regiospecifically mo nofluorinated pyrimidines 4 in good yields. The one-pot procedure star ting from 1 was applicable for synthesizing heterocyclic compounds 4 i n almost comparable yields.