The records of 149 patients who underwent testicular exploration for s
uspected malignancy were reviewed retrospectively. Malignancy was conf
irmed in 102 patients but benign pathology was noted in 47. Patients w
ith benign disease were older, more likely to be Asian, gave a longer
history and on examination were less likely to have a testicular mass.
Increased levels tumour markers, and ultrasonographic and operative a
ppearance of the testis were highly predictive; with ultrasonography h
aving a sensitivity of 100 per cent but a specificity of only 36 per c
ent for malignancy. Preoperative ultrasonography and an awareness of t
he potentially benign nature of many lesions with the use of frozen-se
ction biopsy, where appropriate, may allow a decrease in the currently
high rate of unnecessary orchidectomy without missing testicular mali
gnancy.