Free radicals that appear during physiological processes may lead to a
poptosis in some pathological conditions when antioxidant capacity of
the tissue is surpassed. Additionally, free radicals are involved in t
he control of apoptosis; antioxidant agents suppress apoptosis induced
by a variety of stimuli. The possibility that apoptosis is regulated
by modulation of the levels of free radicals is discussed. (C) 1996 Ac
ademic Press, Inc.