TRANSFERABLE RESISTANCE TO CEFOTAXIME IN NOSOCOMIAL KLEBSIELLA-PNEUMONIAE AND ESCHERICHIA-COLI STRAINS DUE TO THEIR PRODUCTION OF EXTENDED-SPECTRUM BETA-LACTAMASE IN SLOVAKIA

Authors
HUPKOVA M BLAHOVA J BABALOVA M KRCMERY V KRALIKOVA K
Citation
M. Hupkova et al., TRANSFERABLE RESISTANCE TO CEFOTAXIME IN NOSOCOMIAL KLEBSIELLA-PNEUMONIAE AND ESCHERICHIA-COLI STRAINS DUE TO THEIR PRODUCTION OF EXTENDED-SPECTRUM BETA-LACTAMASE IN SLOVAKIA, Journal of chemotherapy, 7(1), 1995, pp. 16-20
Citations number
NO
Categorie Soggetti
Oncology,"Pharmacology & Pharmacy
Journal title
Journal of chemotherapy → ACNP
ISSN journal
1120009X
Volume
7
Issue
1
Year of publication
1995
Pages
16 - 20
Database
ISI
SICI code
1120-009X(1995)7:1<16:TRTCIN>2.0.ZU;2-I
Abstract
Transferable resistance to cefotaxime was demonstrated in 21 nosocomia l strains of Klebsiella pneumoniae and Escherichia coli subsequently i solated from patients in two large University clinics. Using the doubl e-disk diffusion test, we could detect, in each such strain, as well a s in E. coli 3110 K-12 transconjugants after the transfer, the product ion of an Extended Spectrum Beta-Lactamase (ESBL). Ceftibuten was demo nstrated to be effective against the majority of strains studied.