Cogan's syndrome consists of non syphilitic interstitial keratitis ass
ociated with vestibuloauditory dysfunction. This syndrome is rare and
very few cases have been reported since Cogan's first characterization
in 1945. We present the case of a 24-year-oldman with a history of re
current access of arthralgia and glomerulonephritis. Bilateral corneal
disease consists of peripheral whitish patchy opacities in deep strom
a. The patient also shows bilateral severe deafness, fever, meningeal
and tetrapyramidal syndrome. Ocular involvement responds well to corti
costeroids therapy but hearing loss is severe and often irreversible.