Dc. Markel et al., EFFECT OF EPIDURAL ANALGESIA ON VENOUS-BLOOD FLOW AFTER HIP-ARTHROPLASTY, Clinical orthopaedics and related research, (334), 1997, pp. 168-174
The effects of postoperative epidural infusions using local anesthetic
and narcotic were assessed in reference to lower extremity blood flow
Nineteen patients who underwent unilateral total hip arthroplasty wer
e randomly assigned to receive a postoperative epidural infusion of ei
ther 5 mu g/ml fentanyl or 5 mu g/ml fentanyl plus 0.125% bupivacaine
at a rate of 10 ml per hour, The infusions were started after complete
resolution of the operative epidural blockade, Femoral venous blood f
low volume and velocity were measured above and below the saphenous ve
in bifurcation using an Acuson #128XP/10 computed sonography system (d
uplex ultrasound) and proprietary software, Femoral venous blood flow
was not affected by the type of infusion and did not increase during t
he study period, However, femoral venous blood flow volume increased 5
0% after active flexion and extension of the foot, 10 times in quick s
uccession, The addition of bupivacaine (a local anesthetic that blocks
sympathetic afferent nerves) to a postoperative epidural infusion doe
s not augment blood flow from the deep veins of the leg after total hi
p arthroplasty. Alternatively, lower extremity skeletal muscle activit
y significantly enhances femoral venous blood flow and may be a useful
adjunct in deep venous thrombosis prevention.