GENOMIC ORGANIZATION OF HUMAN HISTO-BLOOD GROUP ABO GENES

Authors
YAMAMOTO F MCNEILL PD HAKOMORI S
Citation
F. Yamamoto et al., GENOMIC ORGANIZATION OF HUMAN HISTO-BLOOD GROUP ABO GENES, Glycobiology, 5(1), 1995, pp. 51-58
Citations number
51
Categorie Soggetti
Biology
Journal title
Glycobiology → ACNP
ISSN journal
09596658
Volume
5
Issue
1
Year of publication
1995
Pages
51 - 58
Database
ISI
SICI code
0959-6658(1995)5:1<51:GOOHHG>2.0.ZU;2-B
Abstract
We have isolated human genomic DNA clones encompassing 30 kbp of the h isto-blood group ABO locus. The locations of the exons have been mappe d and the nucleotide sequences of the exon-intron boundaries have been determined. The human ABO genes consist of at least seven exons, and the coding sequence in the seven coding exons spans over 18 kb of the genomic DNA, The exons range in size from 28 to 688 bp, with most of t he coding sequence lying in exon 7.