PIGMENTED VILLONODULAR SYNOVITIS - MONOCLONALITY AND METASTASIS - A CASE FOR NEOPLASTIC ORIGIN

Authors
CHOONG PFM WILLEN H NILBERT M MERTENS F MANDAHL N CARLEN B RYDHOLM A
Citation
Pfm. Choong et al., PIGMENTED VILLONODULAR SYNOVITIS - MONOCLONALITY AND METASTASIS - A CASE FOR NEOPLASTIC ORIGIN, Acta orthopaedica Scandinavica, 66(1), 1995, pp. 64-68
Citations number
15
Categorie Soggetti
Orthopedics
Journal title
Acta orthopaedica Scandinavica → ACNP
ISSN journal
00016470
Volume
66
Issue
1
Year of publication
1995
Pages
64 - 68
Database
ISI
SICI code
0001-6470(1995)66:1<64:PVS-MA>2.0.ZU;2-8
Abstract
We report a 48-year follow-up of a case of recurrent pigmented villono dular synovitis of the knee. Subcutaneous metastasis to the contralate ral thigh was an unusual finding. Histology demonstrated fibroblastic and histiocytic proliferation, as well as increased mitotic activity i n recurrent lesions. Cytogenetic analyses demonstrated monoclonality a nd chromosomal abnormalities. Our findings support a neoplastic origin of this lesion.