One hundred microlitres (0.1 ml) of N-butyl cyanoacrylate adhesive was
injected into the inferior cannaliculus of 8 patients with dry eye. T
he adhesive induced total (upper and lower) cannalicular occlusion in
each patient which has not resolved to date (mean follow-up 15.2 month
s, range 11-19 months). Complications were minor and not specific to u
se of this adhesive. It is hoped that its ultimate reversibility will
make the technique suitable for younger patients with dry eye.