Rr. Diehl et P. Berlit, QUANTITATIVE TILT-TABLE EXAMINATION WITH TCD MONITORING IN THE DIAGNOSIS OF NEUROCARDIOGENIC SYNCOPE (VASOVAGAL SYNCOPE), Nervenarzt, 66(2), 1995, pp. 116-123
The clincal significance of quantitative tilt-table examination with T
CD monitoring in the diagnosis of neurocardiogenic syncope is evaluate
d. A 50-year-old male suffered a neurocardiogenic syncope during tilt-
table examination with a strong drop in blood pressure, an increase in
cerebrovascular resistance as evidenced by transcranial Doppler monit
oring, and a 30-s cardiac asystole, followed by a generalized seizure.
No further syncope could be elicited during tilt-table examination af
ter beta-blocker treatment, It was hypothesized that hyperactivity of
the left ventricular mechanoreceptors due to increased force of ventri
cular contraction during a state of reduced venous backstream to the h
eart was responsible for eliciting the neurocardiogenic syncope. Tilt-
table examination with an upright position for at least 45 min enables
the diagnosis of a neurocardiogenic syncope to be made with sufficien
t sensitivity and specificity. Several studies have shown that medicat
ion with beta-blockers is successful in the treatment of neurocardioge
nic syncope. The implantation of cardiac pacemakers should only be con
sidered if medication is not successful.