V. Thiery et al., CONVENIENT SYNTHESIS OF 2-SUBSTITUTED-6 OR 7-ACYLATED-1,4-BENZODIOXINOR 2,3-DIHYDRO-1,4-BENZODIOXIN DERIVATIVES, Tetrahedron, 51(9), 1995, pp. 2619-2628
The Friedel-Crafts acylation of 2-substituted-1,4-benzodioxin derivati
ves provides regioselectively the 6-acyl compounds. The same reaction
with the saturated analogs affords two regioisomers with the 7-acyl co
mpounds as the main products.