PREVALENCE OF HEPATITIS-B MARKERS AND MEASLES, MUMPS, AND RUBELLA ANTIBODIES AMONG JEWISH REFUGEES FROM THE FORMER SOVIET-UNION

Objective.-To assess the prevalence of hepatitis B virus (HBV) infecti on and immunity to measles, mumps, and rubella among refugees from the former Soviet Union (FSU). Design.-Descriptive study. Setting.-Soviet Immigrant Health Care Program, Sinai Samaritan Hospital, Milwaukee, W is. Patients.-Consecutive sample of 496 Jewish refugees from the FSU p resenting for new arrival screening from December 1, 1990, through Jan uary 11, 1993. Outcome Measures.-Hepatitis B surface antigen (HBsAg), hepatitis B core antibody, hepatitis B surface antibody, and measles, mumps, and rubella antibodies. Results.-At least one hepatitis B marke r was detected in 22% of the refugees, and HBsAg was detected in 0.4%. The rate of HBV infection (any marker present) increased with increas ing age, ranging from 4% among those aged 0 through 19 years to 31% am ong those aged 50 through 59 years (chi(2) test for trend, 13.5; P<.00 1). Among those aged 0 through 19 years, 19% lacked antibody to measle s, 8% lacked antibody to mumps, and 13% lacked antibody to rubella. Re fugees who were less than 30 years of age were more than twice as like ly to lack antibodies to measles, mumps, or rubella compared with thos e who were 30 years of age or older (relative risk, 2.8; 95% confidenc e interval, 1.8 to 4.2; P<.001). Conclusions.-In our sample of Jewish refugees from the FSU (primarily Ukraine, Russia, and Belorussia), the rate of HBsAg positivity was low, suggesting that routine screening f or HBV infection is not needed. Seronegativity to measles, mumps, and rubella was relatively common among those less than 30 years old. Thos e refugees who were born after 1957 should be given combined measles, mumps, and rubella vaccine unless their written documentation indicate s previous receipt of these antigens according to the immunization sch edule recommended in the United States.