Present knowledge of the biology and distribution of Toxoplasma gondii
allows to provide recommendations for primary prevention of infection
with the parasite. The recommendations are chiefly designed for ''ser
onegative'' pregnant women without specific serum anti-T-gondii-IgG an
d for persons with continuous or temporary immune deficiencies. Preven
tion should focus on 3 main sources of infection risk: Meat: meat shou
ld only be eaten when well cooked or when it has been frozen prior to
preparation; do not prepare raw food in the same place and with the sa
me utensils as for raw meat preparation; no mouth-finger-contact while
handling raw meat. Environment: fruit and vegetables should be carefu
lly washed prior to consumption (also including fruit and vegetables f
rom the consumer's own garden or orchard). Cats: household cats should
be preferably fed with canned food rather than with raw meat; contact
with any utensil which may have been contaminated by cat's feces, as
well as with the cat's litter, must be strictly avoided. If cleaning t
he cat's toilet is inevitable, plastic gloves must be worn. Disinfect
the cat's toilet daily with boiling water. All primary prevention meas
ures apply also to the areas of agriculture, veterinary practices, pet
shops and gastronomy. Secondary prevention by means of serological mo
nitoring of seronegative pregnant women can only be envisaged when ass
ociated with precise primary prevention recommendations.