CONGENITAL TOXOPLASMOSIS - THE PEDIATRICI ANS APPROACH

The first part of this paper reviews: (1) the spectrum of clinical fea tures of congenital toxoplasmosis; (2) the natural course of fetal inf ection; (3) the influence of antitoxoplasma therapy on the course of t he disease; (4) methods for diagnosing the toxoplasma infection and as sessing the severity of the disease; (5) currently used antitoxoplasma drugs and different therapeutic regimens. The second part suggests a practical approach to the problem of congenital toxoplasma infection, including diagnostic work-up, drug therapy, and follow-up. This practi cal approach is modulated according to the clinical syndrome in the in fant and diagnostic and therapeutic considerations in the mother.