REDUCTIVE FORMATION OF 3-BENZOYLAMINOPYRROLO[2,1-A]ISOQUINOLINES FROM1-[(1,2,4-OXADIAZOL-3-YL)ETHYL]ISOQUINOLINES

Authors
BATA I KORBONITS D HEJA G KOLONITS P SIMON K
Citation
I. Bata et al., REDUCTIVE FORMATION OF 3-BENZOYLAMINOPYRROLO[2,1-A]ISOQUINOLINES FROM1-[(1,2,4-OXADIAZOL-3-YL)ETHYL]ISOQUINOLINES, ACH, models in chemistry, 131(3-4), 1994, pp. 351-362
Citations number
19
Categorie Soggetti
Chemistry
Journal title
ACH, models in chemistry → ACNP
ISSN journal
12178969
Volume
131
Issue
3-4
Year of publication
1994
Pages
351 - 362
Database
ISI
SICI code
1217-8969(1994)131:3-4<351:RFO3F>2.0.ZU;2-T
Abstract
Catalytic hydrogenation of diazol-3-yl)ethyl]-1,2,3,4-tetrahydroisoqui nolines (9) gave 3-benzimidopyrrolo[2,1-a]isoquinolines (11) by reduct ive cleavage of the N-O bond of the oxadiazole ring and subsequent eli mination of ammonia. A mixture of 3-benzamidopyrrolo[2,l-a]isoquinolin e (18) and 11 was formed from the corresponding 3,4-dihydroisoquinolin e derivatives (16) in a similar route.