F. Sauter et al., SYNTHESES OF FULLY AROMATIC PYRIDO[4',3' 4,5]THIENO[2,3-D]PYRIMIDINIEDERIVATIVES/, ACH, models in chemistry, 131(3-4), 1994, pp. 489-498
Reaction of N-protected 4-piperidones with sulfur and cyanacetamide ga
ve thieno[2,3-c] pyridine derivatives which were cyclized to tetrahydr
o-pyrido[4',3':4,5]thieno[2,3-d] pyrimidines. Subsequently the pyrido
moiety of these products was aromatized. The products thus obtained we
re used to prepare pyrido[4',3' :4,5]thieno[2,3-d]pyrimidine-4-amines.