COEXISTENCE OF SCLEROMYOSITIS ASSOCIATED WITH PM-SCL ANTIBODY AND MYASTHENIA

Myasthenia gravis coexists in about 15% of the cases with other autoim mune diseases. Association with polymyositis or dermatomyositis is ver y rare, although myasthenic reaction is not infrequent in typical poly myositis and myopathic changes may occur in cases of myasthenia. This is the first case of coexistence of myasthenia and scleromyositis, ass ociated with PM-Scl antibody as an immune marker. The patient was foun d to have persistent thymus. Myasthenia preceded scleromyositis for 9 yr, was at periods asymptomatic, and recurred simultaneously with deve lopment of scleromyositis. Scleromyositis should be added to the list of autoimmune disorders coexistent with myasthenia.