CRYSTAL AND MOLECULAR-STRUCTURE OF 17-OXOLUPANINE

C15H22N2O2 has been studied by X-ray diffraction. It crystallizes in o rthorhombic system in space group P2(1)2(1)2(1) With Z = 4 and unit ce ll dimensions: a = 7.320(1), b = 8.602(2), c = 22.570(5) Angstrom. The structure was refined to an R = 0.054 and R(w) = 0.067 for 956 observ ed structure amplitudes. The two quinolizidine systems have quasi-tran s and quasi-ris configurations. The piperidine (A, B, C, D) rings of t he molecule have half-chair, chair, sofa and chair conformations, resp ectively.