Me. Boczar et al., A TECHNIQUE REVISITED - HEMODYNAMIC COMPARISON OF CLOSED-CHEST AND OPEN-CHEST CARDIAC MASSAGE DURING HUMAN CARDIOPULMONARY-RESUSCITATION, Critical care medicine, 23(3), 1995, pp. 498-503
Objective: To compare the hemodynamics of closed-chest cardiac massage
vs, open-chest cardiac massage in patients resuscitated from cardiac
arrest that occurred outside of the hospital. Design: Prospective, non
-outcome, case series. Setting: Large urban emergency department. Pati
ents: Ten adult, normothermic, nontraumatic, out-of-hospital, cardiac
arrest patients who failed advanced cardiac Life support (ACLS) therap
y. Interventions: Patients presenting to the hospital in cardiac arres
t were managed according to the ACLS protocol at the clinician's discr
etion, Proximal aortic and central venous pressure catheters were plac
ed to measure arteriovenous compression- and relaxation-phase pressure
gradients, After 5 mins of baseline measurements during closed-chest
cardiac massage, patients underwent a left lateral thoracotomy, and op
en-chest cardiac massage was performed for 5 mins. Measurements and Ma
in Results: The mean coronary perfusion pressure and compression-phase
pressure gradients were 7.3 +/- 5.7 and 6.2 +/- 5.4 mm Hg, respective
ly, during closed-chest cardiac massage, while increasing to 32.6 +/-
17.8 and 32.6 +/- 29.9 mm Hg, respectively, during open-chest cardiac
massage, The differences between both measurements were statistically
significant (p < .05). Conclusions: Open-chest cardiac massage is supe
rior to closed-chest cardiac massage in providing relaxation-phase and
compression-phase pressure gradients during cardiac arrest in patient
s failing current ACLS protocols, During open-chest cardiac massage, a
ll patients exceeded the minimum coronary perfusion pressure of 15 mm
Hg, which is recommended to obtain a return of spontaneous circulation
, Further outcome studies are needed to determine the timeliness and a
ppropriate indications for open-chest cardiac massage.