3-PYRIDINES AS REPLACEMENTS FOR AN ISOXAZOLE RING - THE ANTIRHINOVIRAL ACTIVITY OF PYRIDINE ANALOGS RELATED TO DISOXARIL

Authors
BAILEY TR DIANA GD DRAPER TL VESCIO N NITZ TJ PEVEAR DC DUTKO FJ
Citation
Tr. Bailey et al., 3-PYRIDINES AS REPLACEMENTS FOR AN ISOXAZOLE RING - THE ANTIRHINOVIRAL ACTIVITY OF PYRIDINE ANALOGS RELATED TO DISOXARIL, Bioorganic & medicinal chemistry letters, 5(9), 1995, pp. 985-990
Citations number
12
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Medicinal
Journal title
Bioorganic & medicinal chemistry letters → ACNP
ISSN journal
0960894X
Volume
5
Issue
9
Year of publication
1995
Pages
985 - 990
Database
ISI
SICI code
0960-894X(1995)5:9<985:3ARFAI>2.0.ZU;2-7
Abstract
In a series of rhinovirus inhibitors related to Disoxaril, replacement of 3-methylisoxazole with all 3 isomers of pyridine showed the 3-pyri dyl isomer most similar to 3-methylisoxazole in spectrum of activity o ver 15 human rhinovirus serotypes.