SYNTHESIS AND PHARMACOLOGICAL EVALUATION OF A NOVEL SERIES OF 5-ARYL BENZIMIDAZOLE ANGIOTENSIN-II RECEPTOR ANTAGONISTS

Authors
PALKOWITZ AD STEINBERG MI ZIMMERMAN KM THRASHER KJ HAUSER KL BOYD DB
Citation
Ad. Palkowitz et al., SYNTHESIS AND PHARMACOLOGICAL EVALUATION OF A NOVEL SERIES OF 5-ARYL BENZIMIDAZOLE ANGIOTENSIN-II RECEPTOR ANTAGONISTS, Bioorganic & medicinal chemistry letters, 5(9), 1995, pp. 1015-1020
Citations number
6
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Medicinal
Journal title
Bioorganic & medicinal chemistry letters → ACNP
ISSN journal
0960894X
Volume
5
Issue
9
Year of publication
1995
Pages
1015 - 1020
Database
ISI
SICI code
0960-894X(1995)5:9<1015:SAPEOA>2.0.ZU;2-#
Abstract
A novel series of benzimidazole angiotensin II (Ang II) receptor antag onists (4, 13, 5, 17) were synthesized and compared pharmacologically to the previously described imidazole analogues (1 3a-b).